a tool for identifying drug-targetable redox-active disulphides

Interferon tau-1

Intramolecular

Cysteine 24 and cysteine 122

A redox-regulated disulphide may form within Interferon tau-1 between cysteines 24 and 122 (1 and 99 respectively in this structure).

Details

Redox score ?

90

PDB code

Structure name

ovine interferon tau

Structure deposition date

1999-01-07

Thiol separation (Å)

2

Half-sphere exposure sum ?

nan

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

24

Residue number B

122

Peptide name

Interferon tau-1

Ligandability

Cysteine 24 of Interferon tau-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 122 of Interferon tau-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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